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For animal studies quality assessment was performed using SYRCLEs risk of bias tool ( Results Out of a total of 1436 identified unique records ( Figure 1 ), we excluded 1372 records for not meeting the inclusion criteria based on title or abstract or upon further evaluation of the full text
The question is whether the marginal extra response justifies the marginal extra side effect risk and cost
The FDA has also taken it off the drug shortage list, which suggests a similar set of rules on compounding will apply to semaglutide
doi: 10.1056/NEJMoa1411892
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Kybella Phase III REFINE-1 trial JAMA Dermatology, 2015 3
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