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To further explore this citrate method Bally et al., studied the effect of proton gradient by replacing the intraliposomal solution to HEPES buffer pH (7.0) from 300 mm citrate buffer (pH 4.0), keeping the internal pH undisturbed
Trial of Lixisenatide in early Parkinson's disease
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It can help alleviate gastrointestinal side effects like nausea and constipation and prevent dehydration, which can sometimes lead to kidney issues
doi: 10.1016/j.lanepe.2025.101426
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