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Among the patients who took lorcaserin and achieved a 5% or more weight loss after 1 year, more patients who continued taking lorcaserin during the second year (67.9%) were able to maintain their weight loss compared to those who received the placebo during the second year (50.3%)

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However, the individual evidence for each compound is so robust, and the mechanisms so complementary, that the case for combining them is strong

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