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There are over 20 identified gut peptides within the GI tract, many of which play a key role in energy and glucose homeostasis, with the following sections focusing on the incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), CCK, and several others
Trulicity (dulaglutide) Trulicity (dulaglutide) is an injectable GLP-1 receptor agonist used to improve blood sugar control in adults with type 2 diabetes
The FDA has issued multiple rounds of warning letters to telehealth companies for marketing claims about compounded GLP-1 products that, in the agency's view, implied equivalence to FDA-approved medications or obscured the identity of the actual compounder
Simultaneously, GLP-1 suppresses glucagon secretion from pancreatic alpha cells, which helps prevent excessive glucose production by the liver
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