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The proportions of subjects with heart failure (all classes) and Class II heart failure were also higher in these three trials than the other trials, while the proportions of subjects with Class III heart failure were higher in SUSTAIN 6 and PIONEER 6 than the other trials

Weiner et al., 1998

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For hair-specific applications, some protocols combine systemic subcutaneous GHK-Cu with direct scalp delivery via mesotherapy, injecting diluted GHK-Cu solution directly into the scalp to maximize follicle-level exposure alongside systemic administration