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We previously demonstrated that PFOS-induced ROS can result in the autophagy-associated apoptosis in RTCs, which can be suppressed by NAC (a ROS scavenger) through the suppression of PFOS-induced ERK1/2 phosphorylation

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We also noticed that TMCA treatment could increase the immunostaining of GLP-1 in these mouse intestinal organoids without affecting their gross morphology (Fig