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Similar to CD3 CAR-positive T cells, CD3 CAR-negative T cells of LTR exhibited significantly increased levels of HK, G6PD, and CPT1A compared to STR (Supplementary Fig

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This reduction in desire for highly palatable food items further underscores the capacity of GLP-1 RA-based interventions to not only suppress appetite but also to selectively modulate food preferences, contributing to sustained dietary changes and weight management

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DOI: 10.1111/bjd.13598 MC1R Selectivity and Receptor Pharmacology Comparative receptor binding studies have confirmed MT-1s preferential activity at MC1R versus the broader receptor profile of MT-2, establishing it as the reference compound for isolated MC1R pathway research