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It is also associated with cardiovascular benefits due to its lipid-lowering and anti-inflammatory effects

American Society for Metabolic and Bariatric Surgery (ASMBS)

In descending order, the medications used included serotonin-norepinephrine reuptake inhibitors (used by 182 patients), gabapentin (155 patients), tricyclic antidepressants (134 patients), trazodone (59 patients), pregabalin (46 patients), muscle relaxants (45 patients), montelukast (26 patients), -blockers (21 patients), aripiprazole (12 patients), histamine 1 or histamine 2 blockers (11 patients), naltrexone (8 patients), amphetamine- or methylphenidate-based stimulants (8 patients), midodrine (7 patients), fludrocortisone (6 patients), non-amphetamine stimulants (4 patients), pyridostigmine (4 patients), -blockers (1 patient), and droxidopa (1 patient)

Data and statistical analysis were performed using GraphPad Prism 10.4.0 (Graphpad Software, Inc., La Jolla CA)

It is naturally released during collagen damage

doi: 10.3389/fimmu.2025.1515390 312 AllegraAMirabileGEttariRPioggiaGGangemiS