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The courts ruling will decide whether compounded tirzepatide remains available, but the larger fight over regulatory control and patient access is far from over

Committee members accepted that argument for six peptides, although several votes were close

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Researchers enrolled 17,604 adults who: were 45 years or older had overweight or obesity (BMI 27) already had heart disease (such as a prior heart attack, stroke, or peripheral artery disease) did not have diabetes Participants were randomly assigned to receive either: semaglutide 2.4 mg weekly, or a placebo (an injection with no active medication) They were followed for about 40 months (over 3 years)

Tirzepatides safety profile, backed by larger trials, shows similar side effects but with proven real-world tolerability

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