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The main risks include: Low protein intake: appetite suppression can make it hard to eat enough to preserve muscle Overly aggressive calorie cuts: slows metabolism and lowers testosterone Reduced strength training intensity: leads to loss of anabolic signaling Micronutrient depletion: common in long-term low-calorie diets In other words, tirzepatide helps with fat loss, but it doesnt protect your muscle on its own

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Weight-loss drug users, on average, regain weight at a rate of 0.4 kilograms per month after they stop taking their weight-loss medications, a review of 63 trials covering more than 9,000 individuals published in the British Medical Journal on Wednesday found

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