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What they found: Erectile response in 80 % of subjects in the Melanotan II group vs 20 % placebo Mean time to erection: 45 minutes Mean duration of erection: 90 minutes Subjectively satisfactory penetrative capability in 70 % Nausea in 50 % of subjects Why it matters: This was the first clinical demonstration of the melanocortin mechanism for erectile function

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The excipients, buffers, and preservatives in each pen are identical batch to batch, tested extensively for stability at various temperatures

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Gut microbiome composition may influence GLP-1 production, though evidence in humans remains preliminary

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