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Shortages of commercial GLP-1 drugs initially opened the door for compounding, but as supply chains recover, the rules are tightening
These products are often referred to as compounded GLP-1 medications. SAHPRAs enforcement action On 23 May 2026, SAHPRA announced that it had intensified enforcement action against the unlawful manufacturing and distribution of unregistered GLP-1 and GIP medicines containing semaglutide, tirzepatide, or combination formulations
This more favorable hormonal milieu explains why GLP-1 weight loss tends to preserve more muscle mass, produce less hunger and psychological distress, and create a more sustainable long-term trajectory than equivalent weight loss from dieting alone
Choosing the right GLP-1 medication depends on your individual tolerance, health history, and how your body responds to different peptide pathways
Never transfer TOUJEO from the cartridges of the TOUJEO SoloStar or TOUJEO Max SoloStar prefilled pen into a syringe for administration [see Warnings and Precautions (5.4)]
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