Cost is the top reason people cant stay on these medicines: in a KFF Health Tracking Poll (2025), more than half of GLP-1 users (56%) said the medicines were difficult to afford , even with insurance, which is why Trimis flat $99$125/month cash price matters
Yet, more recently, a metabolomic analysis reveals the importance of glutamine uptake by ASCT2 and its conversion into ROS-producing intermediate metabolite -Ketoglutarate as marker of sensitivity during sulfasalazine xCT-inhibition cell death in head and neck squamous cells carcinoma (46)
In animal studies, thyroid C-cell tumours have been observed, though the clinical significance in humans remains under investigation
Neurology 369, 114541
and Tiffani Bell Washington, MD, MPH, a child and adolescent psychiatrist and obesity medicine physician, who lives in Boston
Neurology 83 , 22392246 (2014)