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These are long-acting medications designed for once-weekly administration
Cardiovascular Risks: Effects on Heart Rate and Blood Pressure Both Tirzepatide and Semaglutide can affect the heart , though their impact is different
J Nutr 134:489492 Ferrari CK (2012) Effects of xenobiotics on total antioxidant capacity
The standard tirzepatide titration schedule from the FDA label is: 2.5mg for 4 weeks, then 5mg, 7.5mg, 10mg, 12.5mg, and 15mg, each step 4 weeks apart
Focus on protein-rich foods at each meal, as protein promotes satiety and helps preserve lean muscle mass during weight loss
Bottom line Nausea may be the most common side effect of Zepbound, but diarrhea is a close second
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