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Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease

Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, Hufner M, Schmiegel WH

After entering the RBC, glucose is immediately converted to glucose-6-phosphate by hexokinase (HK) and then fueled into the glycolytic pathway or into the PPP [182]

Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling