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Loureiro D, Tout I, Narguet S, Bed CM, Roinard M, Sleiman A, Boyer N, Pons-Kerjean N, Castelnau C, Giuly N, Tonui D, Soumelis V, El Benna J, Soussan P, Moreau R, Paradis V, Mansouri A, Asselah T

Stimulation of Fe 2+ -induced lipid peroxidation in phosphatidylcholine liposomes by aluminium ions at physiological pH

Due to the exhaustion of cellular and extracellular GSH caused by numerous GSH-consuming pathways the severe inflammation and oxidative stress triggered by the viral infection steals GSH from crucial functions like NO-dependent vasodilatation, disallowing the patient of being protected from an inflammation that can become fatal

Therefore, the CS regulation, at both enzymatic and epigenetic levels, plays a pivotal role in tumors, suggesting new druggable pathways for prevention and treatment of human cancer

Inoue N, Watanabe M, Morita M, Tomizawa R, Akamizu T, Tatsumi K, et al

and has served as an adviser for Kyowa-Kirin and Novartis