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SLC25A48 controls mitochondrial choline import and metabolism

Both work by reducing hunger through gut hormone pathways, both require a prescription, and both tend to result in weight regain when stopped

While traditionally considered lower-risk populations, countries like Australia, Japan, and South Korea now report adult obesity rates exceeding 30- 35% in urban areas, coupled with rapidly increasing type 2 diabetes prevalence

Interpretation depends on formulation, exposure, route, population, and the exact endpoint studied

Sources & further reading American Society for Metabolic and Bariatric Surgery

Since obesity is a long-term condition, some people may need ongoing treatment