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Dose adjustments to insulin or sulfonylureas may be necessary

Hypothyroidism can cause symptoms including: Fatigue Feeling cold Dry skin Forgetfulness Constipation Weight gain Muscle soreness Loss of interest in sex Lower voice Depression High cholesterol Causes of Hypothyroidism Hashimotos Disease Hashimotos disease is the most common cause of hypothyroidism

DISCLOSURES Cindy Wassef, Radhika Shah, Mahin Alamgir, Samantha Ouellette, and Giulia Frias have no conflicts of interest to disclose

This symptom only exists in 2% of people

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621 TRPA1 antagonist ISC 17536: ISC 17536 is a potent and selective antagonist targeting TRPA1