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Bibcode:2005Natur.438...90C
Is This Treatment Safe for Everyone
While some patients receive these shots at a clinic, many are advised by their healthcare providers to self-inject at home for convenience and consistency
A 2024 meta-analysis in JCEM, Inositol for Polycystic Ovary Syndrome: Systematic Review and Meta-analysis , found selective metabolic benefits in some contexts, which does not validate MIC injections for universal weight loss
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
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