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The more weight you lose, the harder the rubber band pulls you back towards your set point, requiring greater effort to maintain a calorie deficit
Endocrinology (2008) 149(6):316775
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Persistent or worsening reactions warrant a clinician check
Remember: muscle is the most metabolically active tissue in your body
Schrader says that latter issue was a key factor in the 2022 failure in clinical trials of another patch system, from Boston-based Radius Health
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