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Were comparing results from separate trials with different participants, which has limitations: Different inclusion/exclusion criteria Different trial durations (68 vs 72 weeks) Different geographic populations Different lifestyle intervention protocols What Doctors Say: Most weight loss physicians report that both medications are highly effective

Jan 15 2021;28(5):529-537

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289 One limitation of ASNase therapy, which promotes tumor cell death by systematically lowering the asparagine concentration, is that it impairs ASN requirements in normal immune cells

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