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GHK-Cu is a naturally occurring tripeptide complex made from glycine, histidine, and lysine bound to a copper ion
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury
Endocrinology 152 , 40724079 (2011)
At the same time, GLP-1 drugs have turned into a real tool for treating obstructive sleep apnea in obese patients
Under aerobic conditions, key enzymes involved in energy metabolism in Clostridia are rapidly poisoned by oxygen, and the severe energy deficiency ultimately leads to growth inhibition and even death of the bacteria [114]
Network-based drug repurposing has leveraged betweenness and closeness centrality to rank pathway significance and predict drug-disease associations 33,34 , while centrality metrics have also been used to examine disease co-occurrence and mechanistic overlaps 19,35
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