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Since SPRMs affect basic cell programming in hormone-sensitive tissues (not just the uterus) and are known to change endometrial architecture in novel ways, are they associated with an increased risk for cancer SPRMs are now being administered in Europe, so well be paying close attention to outcomes there
doi: 10.1007/s40263-022-00907-3
Gastroenterology 132(6):21312157
The FDA classifies Thrive GLP-1 as a dietary supplement, not a drug
Its removal from Category 1 means it is moving into the PCAC review pipeline for a definitive determination rather than remaining in the indefinite "under evaluation" holding pattern
At the same time, tirzepatide has an established track record and remains an excellent option for many people seeking physician-guided weight loss
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