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Toxicon 59 , 464471 (2012)
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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs
Only liposomal or specialized delivery systems ensure the molecule reaches your cells intact
Reminder The pathways above describe compound-level research and one preclinical combination study
Bacteriostatic water = sterile water + 0.9% benzyl alcohol The added benzyl alcohol acts as a preservative, so a single reconstituted vial can be drawn from repeatedly instead of needing to be used all at once
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