Frequently Asked Questions Why does tirzepatide's long half-life make once-weekly dosing the standard
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But when you account for the fact that people with obesity have higher baseline rates of depression and anxiety, and when you look at properly controlled comparisons, the signal disappears
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A recently published ACC scientific statement highlighted major findings showing cardiovascular benefits from both semaglutide (GLP1 RA) and tirzepatide (GLP1/GIP RA)including improvements in cardiac structure and functiondemonstrating lower rates of heart failure and major cardiovascular events