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Covalent Drug Liability Studies Helps research teams investigate whether electrophilic intermediates can be trapped or reproduced as glutathione conjugates
2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration
Shi, Advancement Of Science 271, (2012) 10811085
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