While the experimental autoimmune encephalomyelitis (EAE) model is closer to anti-MOG disease in etiology, cuprizone-induced demyelination relies directly on oligodendrocyte death to induce the disruption
Recent studies have demonstrated that a medication commonly prescribed for type 2 diabetes and obesity, glucagon-like peptide-1 receptor agonists (GLP-1RA), plays a role in facilitating retinal neuroprotection, which, in turn, may prevent glaucoma development and progression
The data were analyzed in GraphPad Prism 8 using the one site dose-response stimulation method
At 1.67mg/ml, a 0.25mg dose requires about 0.15ml (15 units)
The 2mg dose is a receptor adaptation phase, not a results phase
Pseudomelanoma: recurrent melanocytic nevus following partial surgical removal