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Circulation 112, 27352752

[35] It has been suggested that suicidal behavior and ideation may be associated with use of GLP-1 receptor agonist medication, but studies in several countries since 2024 do not support this

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After treatment with semaglutide, the T content was significantly reduced and a significant rise in E2 levels was dose dependent, but the content of P did not change significantly

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In preclinical and early human studies, it did not produce meaningful increases in ACTH, cortisol, or prolactin, which distinguishes it from older secretagogues such as GHRP-2 and GHRP-6