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However, further studies on different experimental models, such as non-human primates, and with a range of other chemical inhibitors of sirtuins are required to fully explore the potential of sirtuin inhibitors as HDT for TB
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Reported presentations resemble other forms of DILI and may include fatigue, pruritus, dark urine, and jaundice
Food and Drugs Act (R.S.C., 1985, c
The mechanisms that can account for these effects include PPAR-dependent modulation of proteins involved in the above-mentioned cellular processes 25
For unlicensed products, no validated beyond-use period exists
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