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Laboratory studies reveal TB-500 reduces production of inflammatory mediators including TNF- and IL-1 by 55% while enhancing anti-inflammatory IL-10 and TGF- expression, creating balanced immune responses that clear damaged tissue while supporting regeneration
The cells were grown for 4 days and then incubated with 2 mM EGTA, or with purified bacterial cultures resuspended in Caco-2 growth media
Better for Repeat Studies: The pen format makes repeated dosing schedules easier to manage throughout long-term experiments
After this "Point of Diminishing Returns," higher BACs will result in fewer and fewer positive effects
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