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People taking heartburn medication, such as proton pump inhibitors, are at a higher risk for B12 deficiency and may benefit from alternative therapies to control/eliminate the heartburn or have regular Nutrient IV therapies and/or Vitamin B12 injections Elderly Vegans Vegetarians People with tapeworms Alcoholics Excessive use of antibiotics Excessive use of anti-convulsant medication Daily consumption of Aspirin may increase the risk for vitamin B12 deficiency
Novinscak et al., 2008
88100 60 999 2 33 /OPITAC 125mg C45mg CB6B2 -- OPITAC2250mg 4
Incidence varies by dose and individual factors
The oxidative metabolism of pyruvate is suppressed by heightened expression of pyruvate dehydrogenase kinase
pmid:20208358 51
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