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The same study showed partial protection from cisplatin-induced toxic neuropathy a common chemotherapy side effect (Catania et al., 2003)

Ranganathan P

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One group of researchers found that AOM-treated mice have disruptions of occludin, claudin-5, zona occludens-1, and zona occludens-2 protein expression as assessed with western blots

While LipRSV reduced oxidative markers in the hippocampus, cerebellum and posterior cortex, the increase observed in the frontal cortex suggests that nanocarrier distribution and local redox balance may critically influence therapeutic outcomes