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Acknowledgments We would like to express our sincere gratitude to Professor Qiulun Lu and the members of his laboratory for their invaluable support in providing the necessary equipment and technical assistance for this study

It has been hypothesized that short peptides represent an intermediary level of regulation, bridging the gap between small molecules and larger protein complexes

The fourth equatorial position is occupied by an exchangeable ligand (water or a carboxylate from the lysine -carboxyl, depending on pH and ionic conditions)

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