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Exendin-4 (E4), a long-acting GLP-1RA, has demonstrated neuroprotective effects in early experimental DR [49, 50]

Novo Nordisk has not studied its GLP-1 drugs for use in lymphedema treatment, the company tells TODAY.com in a statement, pointing to the FDA-approved indications for its medications

FDA prescribing information for some GLP-1 receptor agonists advises considering discontinuation for sustained increases in resting heart rate

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J Altern Complement Med 17:827833 Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E, Butterfield DA, Morley JE (2003) The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice