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J Biol Chem 288 (29): 2116121172
Plasma levels of malondialdehyde (MDA) were substantially higher and melatonin levels were substantially lower in smokers than non-smokers, which appears that melatonin can lessen the respiratory system damage caused by free radicals brought on by cigarette smoke (67)
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In this case, examining the safety and efficacy of a combination therapy approach, higher doses, injectable administration or earlier intervention may be worthwhile
Bibcode:2005MRFMM.571..121A
That's one of the reasons some people are cautious about taking growth hormone
