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Participants were male and female adults aged 18 years who were of non-childbearing potential and met the BMI inclusion criteria of either 30.0 kg/m, or 27.0 kg/m with hypertension or dyslipidemia
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved for type 2 diabetes management, chronic weight management, and in the case of Wegovy, cardiovascular risk reduction in certain patients
The effects of GLP-1RAs on thyroid cancer risk Multiple retrospective observational studies and spontaneous case reports suggest a possible association between GLP-1RAs and an elevated risk of thyroid cancer [20, 21]
Experimentally, periodically interrupted or long-lasting administration of an A 2A R antagonist such as SCH58261 combined with L-DOPA may restore normal motor function in PD animal models [23]
But we generally dont prescribe medications primarily indicated for metabolic conditions
[24] It is being evaluated for use in the treatment of Parkinson's disease
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