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Male rats receiving 1.2 mg/kg sertraline cumulatively until postnatal day 126 exhibited significantly reduced male potency (based on various indices of mating and fertility), while cumulative treatment significantly increased the number of fetal congenital malformations and reduced the numbers of implantation sites and surviving fetuses

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Peters, A

The original sleep research used IV infusion at nanomolar concentrations

Tendons receive significantly less blood flow than muscle, which is why they heal slowly

Now, this still remains somewhat of a mystery