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Studies show that patients taking Wegovy achieve an average weight loss of 15% from the initial body weight (35 lbs in people with a starting weight of 232 lbs) after 68 weeks (1 year 4 months) on the drug
Clinical trial data from SURMOUNT-1 shows that the 2.5 mg dose produces minimal weight reduction on its own, which is expected since this dose is specifically labeled as an initiation dose rather than a maintenance dose
New approaches are showing what sustainable obesity care can look like in practice
Earlier secretagogues such as GHRP-6 and GHRP-2 do trigger GH release, but they also switch on other pathways: they can raise cortisol (a stress hormone), raise prolactin, and drive a strong hunger response
Kumar, A., & Das, S
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