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A study (98) demonstrated that GGT1 and GGT7 stimulate induction of ER stress-related protein, CHOP-10 and immunoglobulin heavy chain binding protein BiP, indicating specific roles for these GGT protein subtypes in ER stress response
Alternatives include other GLP-1 receptor agonists (such as dulaglutide or liraglutide), SGLT2 inhibitors (such as dapagliflozin or empagliflozin), DPP-4 inhibitors, or insulin therapy
Its effects on cancer directly have not been definitively established
Clinical studies used doses in the 90 to 300 mcg range with consistent improvements in delta-wave sleep
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