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Los mecanismos implicados en las acciones beneficiosas de los agonistas del receptor de GLP-1 sobre MASLD son indirectos, dada la prctica ausencia de GLP-1R en los hepatocitos, salvo los correspondientes a las clulas T que se asocian con efecto antiinflamatorio9

Additionally, reduced activity of GPX4 impairs the effective clearance of lipid peroxides, ultimately resulting in ferroptosis [36]

Therapies like Tirzepatide represent a major advancement by addressing both glycemic control and body weight, two key contributors to long-term metabolic health

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