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Camilleri M, et al

Tirzepatide and heart failure: In a phase III trial, tirzepatide has demonstrated significant benefits in obese patients with heart failure, reducing the risk of major complications, including urgent heart failure visits, hospitalisations, increased diuretic treatment, and cardiovascular-related deaths, by 38% compared to placebo

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Inactive ingredients, formulation, route of administration in some cases, and regulatory pathway differ

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Patients with previous reactions to other incretin-based therapies should discuss this with their healthcare provider, who may consider specialist advice before prescribing tirzepatide