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The dihydroxyacetone, or DHA, is a plant-derived sugar commonly used in self-tanners to give the skin a gradual tan without UV exposure
Many patients experience partial improvement, only to relapse when activity resumes
Each control sample was analyzed in parallel with one patients sample at least
It has been demonstrated that GPX4 is significant in protecting Treg cells from undergoing lipid peroxidation and ferroptosis, thereby contributing to maintaining immune homeostasis (Xu et al., 2021)
For instance, the downregulation of GPx4 has been correlated with the manifestation of radiation injury in various tissues including the intestine, hemopoietic system, lung, cardiovascular system, ovary, and skin of the murine model though enhancing the ferroptosis mode of cell death [67]