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If you think a B12 deficiency may be behind how you have been feeling, the safe first step is to get tested
For at least 20 years, pharma companies led by Novo Nordisk and Eli Lilly have been trying to find a better alternative
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Those with seizure disorders should be especially cautious, as acetyl-L-carnitine may potentially increase seizure frequency in susceptible individuals
Groups at increased risk of B12 deficiency include: Vegans and strict vegetarians , who avoid all animal products and are at significant risk without supplementation or fortified foods Older adults , in whom reduced stomach acid production impairs B12 absorption People with pernicious anaemia , an autoimmune condition that destroys intrinsic factor-producing cells Those who have undergone gastric surgery , including bariatric procedures, which can reduce intrinsic factor availability Individuals taking long-term metformin for type 2 diabetes, as this medication is associated with reduced B12 absorption the MHRA has issued specific safety advice on monitoring B12 levels in this group [6] [7] People with conditions affecting the small intestine , such as Crohn's disease or coeliac disease Symptoms of B12 deficiency can include fatigue, weakness, pins and needles, memory difficulties, and a sore or inflamed tongue (glossitis)
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