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Mice received either vehicle or tirzepatide (0.144 mg/kg, IP) one hour before dark onset, followed by four-hour alcohol access during the dark phase
Injection Site Reactions In ZEPBOUND-treated patients in a pool of Study 1 and 2, injection site reactions were more frequent in those with anti-tirzepatide antibodies (11.3%) compared to those who did not develop anti-tirzepatide antibodies (1%) [see Clinical Pharmacology (12.6)]
Cell type annotation using reference brain atlases 35,36,37 identified all major hippocampal-resident cell populations and, notably, a cluster of infiltrating neutrophils not typically present in healthy brain tissue (Fig
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