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PMID 7804988
It is necessary for sustaining good health since it plays an important part in many physiological processes
The first step consists of the formation of the gamma-glutamylcysteine dipeptide from two substrates: glutamate and cysteine
5-Amino-1MQ is a substrate-mimetic inhibitor occupying the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)
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