semaglutide + cagrilintide and have each been shown to induce weight loss, but how these drugs work in combination in patients with type 2 diabetes and overweight or obesity is unknown. Research findings REDEFINE 1 Trial Finds Cagrilintide–Semaglutide

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At 24 weeks post-cessation: Tapered group: regained 8.2% of body weight Abrupt cessation group: regained 9.7% of body weight Difference: 1.5 percentage points (not statistically significant, p = 0.18) However, the tapered group reported significantly lower hunger scores in weeks 1 to 4 post-cessation (mean visual analog scale score 6.2 vs 7.8, p = 0.003)

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