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Research Background In preclinical research settings, DSIP has been examined across laboratory models, often in the context of: Neuropeptide and hypothalamic signalling studies Sleep-wake cycle and circadian rhythm research models Stress-response and neuroendocrine pathway investigations Published research summaries and references can be accessed via public scientific databases such as PubMed

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Treatment of pernicious anaemia or vitamin B12 deficiency typically involves 1mg injections daily or alternate daily for 1 to 2 weeks meaning the dose is five thousand times smaller than the single dose used in cyanide poisoning, and therefore urinary discolouration is not expected to be observed

Eur Thyroid J 7:167186 Bartalena L, Baldeschi L, Boboridis K et al (2016) The 2016 European Thyroid Association/European Group on Graves Orbitopathy Guidelines for the management of Graves orbitopathy