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doi: 10.1186/s12933-024-02182-6 64 LiangCYuZBaiLHouWTangSZhangWet al

In Figure6 we showed that an overdose of APAP (corresponding to 200 mg/kg, or a 12 g dose for a 60 kg person) depletes liver GSH severely after 2 hours

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in rare cases, this dehydration has been linked to acute kidney injury, as noted in the medicine's UK prescribing information