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In addition to the above mechanism, adsorptive-mediated transcytosis (AMT) is the principal way used for macromolecular transport, which is based on electrostatic interactions between cationic molecules and anionic microdomains present on the membrane of the brain capillary endothelial cells (Lu, 2012)
The effects histone -hydroxybutyrylation on gene expression represents a novel form of epigenetic control
Future research directions include structural optimization, new target development, innovations in delivery technologies, and combination therapy strategies
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