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Evidence gap There is no modern, large-sample, FDA-recognized RCT establishing DSIP's efficacy in any indication

NaBPC157 (administered either in the ng or g/kg range, i.p.) significantly reduced the reactions in the writhing (inflammatory and non-inflammatory, prostaglandin-dependent and independent) and tail pinching tests

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doi: 10.3390/nu15010102 133 GarciaJMSchererTChenJAGuilloryBNassifAPapushaVet al

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In infertile men, the incidence of chromosomal abnormalities has been reported to range from 5 to 15%, indicating that these abnormalities lead to non-obstructive azoospermia (NOA) (17)